Dr. Xiaoran Wang

 Dr. Xiaoran Wang, M.D., Ph.D., Senior lecturer of physiology

Specialties: Electrophysiological studies on neural mechanisms underlying different firing patterns of vasopressin-producing and oxytocin-producing neurons in the hypothalamo-neurohypophysial system; Mg2+-dependent modulation of BKCa channels in arteriolar smooth muscle cell.

 


 Recently, my research interest focuses on differentiating neural mechanisms underlying the firing patterns of magnocellular neuroendocrine neurons in the hypothalamo-neurohypophysial system. A particular research item is to establishing a rat model of hyponatremia and identifying the mechanisms underlying dual response of vasopressin neurons in a hypoosmotic environment.

Representative publications:

Xiao-Yu Liu, Dan Cui, Dongyang Li, Runsheng Jiao, Xiaoran Wang, Shuwei Jia, Dan Hou, Tong Li, Haitao Liu, Ping Wang* and Yu-Feng Wang*. Oxytocin Removes Estrous Female vs. Male Preference of Virgin Male Rats: Mediation of the Supraoptic Nucleus Via Olfactory Bulbs. Frontiers in Cellular. Neuroscience., 23 October 2017

Wang, XiaoranZhao, TingtingZhou, ShanshanSun, LinaZhang, Liming Yu, Guichun Mg(2)(+)-dependent modulation of BKCa channels by genistein in rat arteriolar smooth muscle cells.Journal of Cellular Physiology201422912):1981-1989

Sun, LinaHou, YunlongZhao, TingtingZhou, ShanshanWang, XiaoranZhang, LimingYu, GuichunA combination of genistein and magnesium enhances the vasodilatory effect via an eNOS pathway and BK current amplification.Canadian Journal of Physiology and Pharmacology

Hou, XiaohuaWang, XiaoranZhang, LimingConditional downregulation of brain- derived neurotrophic factor and tyrosine kinase receptor B blocks epileptogenesis in the human temporal lobe epilepsy hippocampus.Neurology India2010581):29-34



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